Adverse effects of steroids on the human body

The first generation of the quinolones began following introduction of the related, but structurally distinct naphthyridine-family nalidixic acid in 1962 for treatment of urinary tract infections in humans. [74] Nalidixic acid was discovered by George Lesher and coworkers in a chemical distillate during an attempt at synthesis of the chloroquinoline antimalarial agent, chloroquine . [75] Naphthyridone and quinolone classes of antibiotics prevent bacterial DNA replication by inhibition of DNA unwinding events, and can be both bacteriostatic and bacteriocidal. [60] (See Mechanism of Action later.) The majority of quinolones in clinical use belong to the second generation class of "fluoroquinolones", which have a true quinoline framework, maintain the C-3 carboxylic acid group, and add a fluorine atom to the all-carbon containing ring, typically at the C-6 or C-7 positions.

The following adverse reactions have been identified during post-approval use of BOTOX. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. These reactions include: abdominal pain; alopecia , including madarosis; anorexia ; brachial plexopathy; denervation /muscle atrophy ; diarrhea; hyperhidrosis; hypoacusis; hypoaesthesia; malaise ; paresthesia ; peripheral neuropathy ; radiculopathy ; erythema multiforme , dermatitis psoriasiform, and psoriasiform eruption; strabismus; tinnitus ; and visual disturbances.

Adverse effects of steroids on the human body

adverse effects of steroids on the human body

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