On top of increasing the production of sebum, steroids may also accelerate the growth of the acne causing bacteria, Propionibacterium acnes , adding to the acne’s severity. It’s advised that the best way to treat steroid-induced acne is to stop taking steroids, but this isn’t always possible. While often associated with body builders, steroids are used for a variety of ailments , such as arthritis, asthma, and severe allergic reactions. In times when you’re unable to stop taking steroids, it’s important to consult your doctor or dermatologist.
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A decrease in the effectiveness of OCPs is a concern with coadministration of oral antibiotics. Although this concern has not been supported by research, some package inserts contain a warning about decreased OCP efficacy with concomitant ampicillin or tetracycline therapy. A review of pharmokinetic data showed a reduction of contraceptive steroid hormones only with concomitant use of rifampin (Rifadin). 24 [Evidence level B, nonquantitative systematic review] Nonetheless, it may be wise to inform patients receiving oral antibiotic therapy about the possibility of OCP failure, and to recommend the use of a second method of contraception.