This obsession has become so common that Dr. Pope has come up with a term for it: Adonis Complex. What fuels it, he says, are the ridiculously outsized bodies purveyed by Hollywood, magazine covers, and even action-toy manufacturers (just check out the size of . Joe these days). "One of the biggest lies being handed to American men today is that you can somehow attain by natural means the huge shoulders and pectorals of the biggest men in the magazines," says Dr. Pope. "Generations of young men are working hard in the gym and wondering what on earth they're doing wrong. They don't realize that the 'hypermale' look that's so prevalent these days is essentially unattainable without steroids."
The illicit anabolic steroid market includes steroids that are not commercially available in the . as well as those which are available. Steroids that are commercially available in the . include fluxoymesterone (Halotestin® ), methyltestosterone, nandrolone (Deca-Durabolin® , Durabolin ® ), oxandrolone (Oxandrin® ), oxymetholone (Anadrol® ), testosterone, and stanozolol (Winstrol® ). Veterinary steroids that are commercially available in the . include boldenone (Equipoise® ), mibolerone, and trenbolone (Revalor® ). Other steroids found on the illicit market that are not approved for use in the . include ethylestrenol, methandriol, methenolone, and methandrostenolone.
Cells of the zona fasciculata and zona reticularis lack aldosterone synthase (CYP11B2) that converts corticosterone to aldosterone, and thus these tissues produce only the weak mineralocorticoid corticosterone. However, both these zones do contain the CYP17A1 missing in zona glomerulosa and thus produce the major glucocorticoid, cortisol. Zona fasciculata and zona reticularis cells also contain CYP17A1, whose 17,20-lyase activity is responsible for producing the androgens, dehydroepiandosterone (DHEA) and androstenedione. Thus, fasciculata and reticularis cells can make corticosteroids and the adrenal androgens, but not aldosterone.