Lung disease: People with this condition often develop emphysema, with
symptoms of a hacking cough, barrel-shaped chest, and difficulty breathing. If
you have this condition and smoke or are exposed to tobacco smoke, it
accelerates the appearance of emphysema symptoms and lung damage.
Liver disease: Alpha-1 antitrypsin deficiency also cause liver disease in some people with the condition, that include liver cancer, cirrhosis of the liver, an abnormally large liver (hepatomegaly), liver failure, and hepatitis. Liver damage from alpha-1 antitrypsin deficiency causes symptom of a swollen abdomen, swollen legs or feet, and jaundice.
Treatment of AATD depends upon the severity of symptoms. FDA approved drug for AATD is an orphan product called alpha-1-proteinase inhibitor (human), sold under the brand name "Prolastin."
After 2 months, we had to fight and beg for X-Rays. My left lung hurt so much. Finally my voice slowly came back. It took til June until people could understand me on the phone. A doctors office called me in June to make an appointment. They hung up and called about an hour later, saying that their phone system wasn’t working well. They had a tech look at the system, and he was scheduled to come back and find out what was wrong. I finally convinced the appointment rep that it was me, and not the phones. By that time, they could hear most of my words, but electronics and hearing aids picked up and magnified the sketchy breathing.
Acute bronchitis, as the term implies, is a lower respiratory tract syndrome and another common source of acute cough. It manifests as a persistent cough, with or without sputum production, in patients with a normal chest radiograph. Although it is much less prevalent than the common cold, acute bronchitis is the most common diagnosis given to patients presenting to a physician with acute cough. It is caused by a respiratory virus more than 90% of the time. Viral cultures and serologic assays are not routinely ordered; hence, the organism responsible is rarely identified.