Liver disease can be prevented by following the right lifestyle and diet. Vaccinations that protect from Hepatitis A and Hepatitis B are widely available. Weight control, giving up smoking and alcohol, exercising regularly and a well-balanced diet will reduces the chances of developing a liver disease. Awareness about liver diseases must be increased. The causes and the complications of a liver disease need to be highlighted. The medications that lead to a liver disease also need to be stopped or their intake must be controlled and minimal. For instance, an overdose of acetaminophen or Tylenol will invariably cause a liver failure. Therefore one must never indulge in self medication.
Cells of the zona fasciculata and zona reticularis lack aldosterone synthase (CYP11B2) that converts corticosterone to aldosterone, and thus these tissues produce only the weak mineralocorticoid corticosterone. However, both these zones do contain the CYP17A1 missing in zona glomerulosa and thus produce the major glucocorticoid, cortisol. Zona fasciculata and zona reticularis cells also contain CYP17A1, whose 17,20-lyase activity is responsible for producing the androgens, dehydroepiandosterone (DHEA) and androstenedione. Thus, fasciculata and reticularis cells can make corticosteroids and the adrenal androgens, but not aldosterone.